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Study identifier: NCT05423587 Synced from ClinicalTrials.gov · July 29, 2026
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Genicular Artery Embolisation for Knee Osteoarthritis II

Condition: Knee Osteoarthritis  ·  Sponsor: Varian, a Siemens Healthineers Company

PhaseNA
Planned participants110
Who can joinAll sexes, 45 Years to no upper limit
Healthy volunteersNo

About this study

This clinical study is designed as a double-blind sham controlled randomised trial with the option of sham group crossover to receive the GAE treatment at 6 months after unblinding. This study will determine if embolisation of abnormal neovasculature arising from branches of the genicular arteries reduces pain in patients with knee osteoarthritis. The study patient population will consist of up to 110 subjects with knee pain for at least 3 months that is resistant to conservative treatment measures. Subjects will be treated with knee embolisation or 2 mL of saline in the sham arm. At 6 months, all subjects in the sham arm will be allowed to cross-over and receive the embolisation procedure with a follow-up duration of 18 months. The total planned study duration is 3.5 years.

This description comes directly from the study's public registry record.

Talk to the study team

Heike S Hausen, MD  ·  2068903102  ·  Heike.Hausen@varian.com

Kate Pietrovito  ·  +19782908408  ·  Kathleen.Pietrovito@varian.com

Always discuss trial participation with your own doctor first.

Locations (1)

Royal Berkshire NHS Foundation TrustReading, United KingdomRecruiting

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Source record: clinicaltrials.gov/study/NCT05423587