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Study identifier: NCT05421273 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Effects of Active Versus Passive Recharge Burst Spinal Cord Stimulation on Pain Experience in Persistent Spinal Pain Syndrome Type 2: a Multicenter Randomized Trial (BURST-RAP Study)

Condition: Persistent Spinal Pain Syndrome Type 2 · Failed Back Surgery Syndrome  ·  Sponsor: Rijnstate Hospital

PhaseNA
Planned participants96
Who can joinAll sexes, 18 Years to 70 Years
Healthy volunteersNo

About this study

Spinal cord stimulation (SCS) has shown to be an effective treatment for patients with persistent spinal pain syndrome Type 2 (PSPS Type 2). The method used to deliver electrical charge in SCS is important. One such method is burst stimulation. Two variations of burst waveforms are currently in use: one that employs active recharge and one that uses passive recharge. It is still unknown if there are clinical differences between active recharge and passive recharge burst SCS. To date, no clinical studies have been performed that directly compared these two burst stimulation waveforms. The objective of this Randomized Clinical Trial (RCT) is to assess and compare effect of passive recharge burst SCS with active recharge burst SCS on pain relief and motivational-emotional facets of pain

This description comes directly from the study's public registry record.

Talk to the study team

Martijn Mons, Msc.  ·  +31433881034  ·  m.mons@maastrichtuniversity.nl

Jan-Willem Kallewaard, PhD  ·  jkallewaard@rijnstate.nl

Always discuss trial participation with your own doctor first.

Locations (6)

Rijnstate HospitalArnhem, Gelderland, NetherlandsRecruiting
Bravis HospitalRoosendaal, North Brabant, NetherlandsRecruiting
Elizabeth TweeSteden HospitalTilburg, North Brabant, NetherlandsRecruiting
Amsterdam University Medical Hospitals A-UMCAmsterdam, North Holland, NetherlandsRecruiting
Alrijne HospitalLeiderdorp, South Holland, NetherlandsNot Yet Recruiting
Diakonessen HospitalZeist, Utrecht, NetherlandsRecruiting

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Source record: clinicaltrials.gov/study/NCT05421273