Condition: Dravet Syndrome · Sponsor: Encoded Therapeutics
ENDEAVOR is a Phase 1/2, 2-part, multicenter study to evaluate the safety and efficacy of ETX101 in participants with SCN1A-positive Dravet syndrome aged ≥6 to \<36 months (Part 1A), aged ≥48 months to \<18 years (Part 1B), and aged ≥6 to \<48 months (Part 2). Part 1A follows an open-label, dose-escalation design, Part 1B follows an open-label design, and Part 2 is a randomized, double-blind, sham delayed-treatment control study.
This description comes directly from the study's public registry record.
Encoded Patient Advocacy · +1 (650) 398-4301 · patientadvocacy@encoded.com
Always discuss trial participation with your own doctor first.
| UCSF Benioff Children's Hospitals | San Francisco, California, United States | Recruiting |
| Colorado Children's Hospital | Aurora, Colorado, United States | Recruiting |
| Nicklaus Children's Hospital | Miami, Florida, United States | Recruiting |
| Ann & Robert H. Lurie Children's Hospital of Chicago | Chicago, Illinois, United States | Recruiting |
| Boston Children's Hospital | Boston, Massachusetts, United States | Not Yet Recruiting |
| Mott Children's Hospital | Ann Arbor, Michigan, United States | Recruiting |
| Mayo Clinic | Rochester, Minnesota, United States | Recruiting |
| Duke Children's Hospital & Health Center | Durham, North Carolina, United States | Not Yet Recruiting |
| Nationwide Children's Hospital | Columbus, Ohio, United States | Not Yet Recruiting |
| Oregon Health and Science University (OSHU) | Portland, Oregon, United States | Recruiting |
| Cook Children's Medical Center | Fort Worth, Texas, United States | Recruiting |
| The Royal Children's Hospital | Melbourne, Australia | Recruiting |
+ 2 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT05419492