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Study identifier: NCT05418010 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Natalizumab for the Treatment of People With Inflammatory Demyelination Suggestive of Multiple Sclerosis, or Definite Multiple Sclerosis, at First Presentation (AttackMS)

Condition: Multiple Sclerosis · Clinically Isolated Syndrome of Demyelination  ·  Sponsor: Queen Mary University of London

PhasePhase 2
Planned participants40
Who can joinAll sexes, 18 Years to 55 Years
Healthy volunteersNo

About this study

Multiple Sclerosis (MS) is a chronic inflammatory \& degenerative disease of the central nervous system (CNS) Recent data from the MS Base registry demonstrated an average delay of 152 - 215 days between first presentation and the diagnosis of MS, and more than one year until Disease Modifying Treatment (DMT) begins. Evidence suggests that shutting down inflammation using highly effective DMTs early after diagnosis leads to better long term clinical outcomes The AttackMS trial will test the effect of starting a highly-effective DMT licensed for MS, Tyruko® (Natalizumab 300mg), within a short time - 14 days - after symptom onset.

This description comes directly from the study's public registry record.

Talk to the study team

Klaus Schmierer  ·  +44 20 7882 6246  ·  k.schmierer@qmul.ac.uk

Julia Elizabeth Phillips  ·  attackms@qmul.ac.uk

Always discuss trial participation with your own doctor first.

Locations (2)

Royal London HospitalLondon, United KingdomNot Yet Recruiting
St George's HospitalLondon, United KingdomRecruiting

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Source record: clinicaltrials.gov/study/NCT05418010