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Study identifier: NCT05416164 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

DESCARTES: De-ESCAlation of RadioTherapy in Patients With Pathologic Complete rESponse to Neoadjuvant Systemic Therapy

Condition: Breast Cancer  ·  Sponsor: The Netherlands Cancer Institute

PhaseNA
Planned participants595
Who can joinFemale, 18 Years to no upper limit
Healthy volunteersNo

About this study

This study evaluates whether radiotherapy can safely be omitted in breast cancer patients with T1-2N0 tumors who achieve a pathologic complete response after neoadjuvant systemic therapy and breast-conserving surgery

This description comes directly from the study's public registry record.

Talk to the study team

F.H. van Duijnhoven, MD, PhD  ·  +31(0)20 5126170  ·  f.v.duijnhoven@nki.nl

J.P. van Olmen, Drs  ·  020-5129111  ·  j.v.olmen@nki.nl

Always discuss trial participation with your own doctor first.

Locations (1)

Antoni van LeeuwenhoekAmsterdam, North Holland, NetherlandsRecruiting

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Source record: clinicaltrials.gov/study/NCT05416164