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Study identifier: NCT05415267 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Immunosuppression and COVID-19 Boosters

Condition: COVID-19  ·  Sponsor: Kirby Institute

PhasePhase 3
Planned participants320
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

It is important people receiving immunosuppressive therapy are provided with the best protection against COVID-19 because they are at greater risk of severe illness should they become infected. As severe immunosuppression can reduce the efficacy of COVID-19 vaccination, doctors agree that COVID-19 boosters is are important to maximise the vaccine response in these people. However, we don't currently know the best time to give booster vaccines to people about to start immunosuppressive therapy. This research aims to address this knowledge gap by examining whether the greatest protection is provided by giving the COVID-19 booster just before the immunosuppressive therapy starts or by waiting and giving the booster 6 months after treatment start. At the 6-month timepoint, in many cases the more intensive immunosuppression is often weaning and the immune system is starting to rebuild.

This description comes directly from the study's public registry record.

Talk to the study team

Dianne L Carey, PhD  ·  +61 2 9385 0908  ·  dcarey@kirby.unsw.edu.au

Always discuss trial participation with your own doctor first.

Locations (5)

Blacktown HospitalBlacktown, New South Wales, AustraliaRecruiting
Royal Prince Alfred HospitalCamperdown, New South Wales, AustraliaRecruiting
Concord General Repatriation HospitalConcord, New South Wales, AustraliaRecruiting
St Vincent's Hospital, SydneyDarlinghurst, New South Wales, AustraliaRecruiting
Westmead HospitalWestmead, New South Wales, AustraliaRecruiting

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Source record: clinicaltrials.gov/study/NCT05415267