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Study identifier: NCT05412758 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Augmented Response of Volatile Biomarkers in Assessment of Oesophagogastric Cancer (AROMA 1 / BIORESOURCE)

Condition: Volatile Organic Compounds · Microbiome · Microbioata  ·  Sponsor: Imperial College London

PhaseNA
Planned participants648
Who can joinAll sexes, 18 Years to 90 Years
Healthy volunteersYes

About this study

Cancer of the stomach and oesophagus is among the world's top five cancers. Survival rates are very poor as the disease presents late and early symptoms are non-specific. The study team has developed a non-invasive test for cancers of the stomach and oesophagus based on the detection of volatile organic compounds in exhaled breath. These compounds are known to be produced by both cancers as well as cancer associated bacteria within the gut. The proposed innovation is to improve the accuracy of this test by investigating whether simple metabolic substrates can increase the production of these volatile organic compounds by both the tumour and its associated bacteria.

This description comes directly from the study's public registry record.

Talk to the study team

Ayushi Pabari, BSc, MSc  ·  02075948847  ·  aroma@imperial.ac.uk

Always discuss trial participation with your own doctor first.

Locations (1)

Imperial College NHS Foundation TrustLondon, United KingdomRecruiting

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Source record: clinicaltrials.gov/study/NCT05412758