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Study identifier: NCT05411445 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Study of Role of Blood Microvescicles and Exosomes in Patients With Graft Occlusion After Aortocoronary Bypass Surgery

Condition: Coronary Artery Bypass Surgery  ·  Sponsor: Maria Cecilia Hospital

PhaseN/A
Planned participants300
Who can joinAll sexes, 40 Years to 80 Years
Healthy volunteersNo

About this study

Coronary artery bypass graft (CABG) surgery is still the standard treatment of coronary revascularization for patients with severe coronary artery disease (CAD). Graft patency, together with completeness of revascularization, is a major determinant of long-term outcome following CABG. The surgical procedure elicits a persistent systemic inflammatory response associated with the activation of the hemostatic system leading to perturbation of endothelial and vascular function and activation of platelets and leukocytes. All of these events are the main players responsible for the early and late graft failure in a significant percentage of patients.

This description comes directly from the study's public registry record.

Talk to the study team

Alberto Albertini, MD  ·  +39 0545 217693  ·  aalbertini@gvmnet.it

Elena Tenti  ·  etenti@gvmnet.it

Always discuss trial participation with your own doctor first.

Locations (1)

MCHCotignola, Ravenna, ItalyRecruiting

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Source record: clinicaltrials.gov/study/NCT05411445