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Study identifier: NCT05403047 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Efficacy of Tenofovir Disoproxil on Mother-to-child Transmission of HBV in Tokombéré, Cameroon in Pregnant Women

Condition: Hepatitis B Virus - Chronic Active  ·  Sponsor: ANRS, Emerging Infectious Diseases

PhasePhase 4
Planned participants150
Who can joinFemale, 16 Years to no upper limit
Healthy volunteersNo

About this study

Pregnant women with HBeAg-positive viral hepatitis b or high viral load will receive Tenofovir disoproxil fumarate (TDF) from the 28th week of amenorrhoea until 6 weeks after delivery. Their newborns will receive the hepatitis B vaccine, starting with one dose at birth and followed by three booster doses, according to the Expanded Programme on Immunisation. The investigators hypothesise that a short course of TDF could greatly reduce the risk of HBV MTCT in pregnant women at high risk of MTCT (HBeAg positive or with high viral load).

This description comes directly from the study's public registry record.

Talk to the study team

Maaga DOURWE, MD  ·  0697073424  ·  dourwemaaga2@gmail.com

Always discuss trial participation with your own doctor first.

Locations (1)

Hôpital Privé de TokombéréTokonbéré, CameroonRecruiting

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Source record: clinicaltrials.gov/study/NCT05403047