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Study identifier: NCT05400590 Synced from ClinicalTrials.gov · July 29, 2026
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Comparison of the Healing Properties on Corneal Cells of Groth Factor-enriched Plasma and Autologous Serum From Aniridia Patients

Condition: Aniridia  ·  Sponsor: Fondation Ophtalmologique Adolphe de Rothschild

PhaseN/A
Planned participants24
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersYes

About this study

Keratopathy of patients with aniridia leads to epithelial scarring disorders and a progressive clouding of the cornea linked to this abnormal healing (fibrosis). Treatment with autologous serum is usually undertaken to promote epithelial healing. However, autologous serum does not prevent the formation of fibrosis, whereas growth factor-rich plasma appears to be associated with a reduction in the in vitro expression of fibrosis markers. This study seeks to compare the in vitro healing and anti-fibrotic properties of autologous serum and growth factor rich plasma from aniridia patients and healthy controls.

This description comes directly from the study's public registry record.

Talk to the study team

Amélie YAVCHITZ  ·  (0)1 48 03 64 54  ·  ayavchitz@for.paris

Always discuss trial participation with your own doctor first.

Locations (1)

Hôpital Fondation A. de RothschildParis, FranceRecruiting

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Source record: clinicaltrials.gov/study/NCT05400590