Condition: Psoriasis · Sponsor: Centre Hospitalier Universitaire de Nice
Dendritic cells (DC) paly a key role in the induction and chronicity of psoriasis by capturing the antigenes and activating the T cell repsonse. This activation requires their migration from the cutaneous sensitisation site to the lymph nodes. This migration requires an important intracellular metabolic activity, with a strong involvmenet of glucdic metabolism. This activity is linked with the systemic activity. This study aims to compare the migration and the phenotypic and metabolic caracteristics of blood and skin DCs in patients with or without psoriasis and with or without type 2 diabetes,
This description comes directly from the study's public registry record.
PASSERON Thierry, PhD · +33492036488 · passeron.t@chu-nice.fr
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| CHU de Nice | Nice, Alpes-maritimes, France | Recruiting |
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Source record: clinicaltrials.gov/study/NCT05399433