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Study identifier: NCT05398302 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Image-Guided Biopsies to Identify Mechanisms of Resistance in Patients With Metastatic Castration Resistant Prostate Cancer Treated With 177Lu-PSMA Radioligand Therapy

Condition: Castration-Resistant Prostate Carcinoma · Metastatic Prostate Carcinoma  ·  Sponsor: Jonsson Comprehensive Cancer Center

PhasePhase 1
Planned participants30
Who can joinMale, N/A to no upper limit
Healthy volunteersNo

About this study

This clinical trial studies mechanisms of resistance to 177-lutetium prostate specific membrane antigen (177Lu-PSMA) radioligand therapy using image-guided biopsies in patients with castrate-resistant prostate cancer that had spread to other places in the body (metastatic). Diagnostic procedures, such as image guided biopsies, may help in learning how well 177Lu-PSMA works to kill tumor cells and allow doctors to plan better treatment.

This description comes directly from the study's public registry record.

Talk to the study team

Ankush Sachdeva  ·  310-794-3421  ·  asachdeva@mednet.ucla.edu

Always discuss trial participation with your own doctor first.

Locations (1)

UCLA / Jonsson Comprehensive Cancer CenterLos Angeles, California, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05398302