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Study identifier: NCT05397769 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Envafolimab Plus Chemoradiotherapy for Locally Advanced NPC, a Prospective, Single Armed Phase II Trial.

Condition: Locally Advanced Nasopharyngeal Carcinoma · Envafolimab · Induction Chemotherapy  ·  Sponsor: Sun Yat-sen University

PhasePhase 2
Planned participants36
Who can joinAll sexes, 18 Years to 65 Years
Healthy volunteersNo

About this study

Patients diagnosed with locally advanced nasopharyngeal carcinoma will be recruited in this study. All the patients will get 3 cycles of GP+ Envafolimab for the induction chemotherapy. After that, the patients will receive concurrent chemoradiotherapy. Radiotherapy will be given by IMRT, under the dose of GTVnx 68-70Gy/30-33f, 5d/w,6-7w, during which, every patient would receive 2 cycles of DDP+Envafolimab as concurrent chemotherapy. Then patients would receive Envafolimab every 3 weeks for maintenance treatment for a year, until disease progression or intolerance of treatment. . We aim to evaluate the three years progression free survival of these patients by the combination of Envafolimab with curative chemoradiotherapy.

This description comes directly from the study's public registry record.

Talk to the study team

Fei Han  ·  13822113698  ·  hanfei@sysucc.org.cn

Xiaohui Wang  ·  18826260661  ·  wangxh@sysucc.org.cn

Always discuss trial participation with your own doctor first.

Locations (1)

Sun Yat-sen University Cancer CenterGuangzhou, Guangdong, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT05397769