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Study identifier: NCT05395624 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Safety, PK and Biodistribution of 18F-OP-801 in Patients With ALS, AD, MS, PD and Healthy Volunteers

Condition: Amyotrophic Lateral Sclerosis (ALS) · Parkinson Disease (PD) · Alzheimer Disease (AD)  ·  Sponsor: Ashvattha Therapeutics, Inc.

PhasePhase 1/Phase 2
Planned participants65
Who can joinAll sexes, 18 Years to 80 Years
Healthy volunteersYes

About this study

This is a Phase 1/2 study to evaluate the safety and tolerability of 18F-OP-801 in subjects with ALS, AD, MS, PD and age-matched HVs. 18F-OP-801 is intended as a biomarker for PET imaging of activated microglia and macrophages in regions of neuroinflammation.

This description comes directly from the study's public registry record.

Talk to the study team

Julee Cheung  ·  408-476-4172  ·  jcheung@avttx.com

Always discuss trial participation with your own doctor first.

Locations (3)

UCSFSan Francisco, California, United StatesRecruiting
Stanford UniversityStanford, California, United StatesRecruiting
Mayo Clinic JacksonvilleJacksonville, Florida, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05395624