Condition: Type2Diabetes · ASCVD · Sponsor: Brigham and Women's Hospital
PRECIDENTD is a randomized, open label, pragmatic clinical trial designed to compare rates of the total number of cardiovascular, kidney, and death events among two alternative treatments for patients with type 2 diabetes (T2D) and either established atherosclerotic cardiovascular disease (ASCVD) or at high risk for ASCVD. To accomplish this objective, we will randomly assign 6,000 patients with established T2D and ASCVD or high-risk for ASCVD in a 1:1 allocation to sodium-glucose cotransporter-2 inhibitor (SGLT2i) or glucagon-like peptide-1 receptor agonists (GLP-1RA). Participants will be followed for the occurrence of the trial primary endpoint of the total (first and recurrent) number of episodes of myocardial infarction (MI), stroke, arterial revascularization, hospitalization for heart failure, development of end-stage kidney disease, kidney transplantation, and mortality, counting all events from randomization until end of study.
This description comes directly from the study's public registry record.
Brendan Everett, MD, MPH · 617-732-8790 · PRECIDENTDccc@bwh.harvard.edu
Maureen Malloy · 617-732-8773 · PRECIDENTDccc@bwh.harvard.edu
Always discuss trial participation with your own doctor first.
| Longwood Research LLC | Huntsville, Alabama, United States | Recruiting |
| HonorHealth Research & Innovation Institute | Scottsdale, Arizona, United States | Recruiting |
| Eastside Clinical Research Associates | Los Angeles, California, United States | Recruiting |
| Kendall South Medical Center, Inc | Miami, Florida, United States | Recruiting |
| South Florida Research Solutions, LLC | Pembroke Pines, Florida, United States | Recruiting |
| NSC Research, Inc. | Johns Creek, Georgia, United States | Recruiting |
| Herman Clinical Research | Suwanee, Georgia, United States | Recruiting |
| University of Illinois Chicago | Chicago, Illinois, United States | Recruiting |
| Rush University Medical Center | Hinsdale, Illinois, United States | Recruiting |
| University of Iowa | Iowa City, Iowa, United States | Recruiting |
| University of Kansas Medical Center | Fairway, Kansas, United States | Recruiting |
| Johns Hopkins School of Medicine | Baltimore, Maryland, United States | Recruiting |
+ 24 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT05390892