← Eichor
Study identifier: NCT05387954 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

PFO Closure, Oral Anticoagulants or Antiplatelet Therapy After PFO-associated Stroke in Patients Aged 60 to 80 Years

Condition: Cryptogenic Ischemic Stroke · Patent Foramen Ovale  ·  Sponsor: Assistance Publique - Hôpitaux de Paris

PhasePhase 3
Planned participants792
Who can joinAll sexes, 60 Years to 80 Years
Healthy volunteersNo

About this study

To assess whether PFO closure plus antiplatelet therapy is superior to antiplatelet therapy alone and whether oral anticoagulant therapy is superior to antiplatelet therapy to prevent stroke recurrence in patients aged 60 to 80 years with a PFO with large shunt (\> 20 microbubbles) or a PFO associated with an ASA (\> 10 mm), and an otherwise unexplained ischemic stroke.

This description comes directly from the study's public registry record.

Talk to the study team

Carla Vandenabele  ·  +331 44 84 57 27  ·  carla.vandenabele@aphp.fr

Malha Berrah  ·  malha.berrah@aphp.fr

Always discuss trial participation with your own doctor first.

Locations (42)

CHU AmiensAmiens, FranceRecruiting
Centre Hospitalier de la Côte BasqueBayonne, FranceRecruiting
CHU Jean MinjozBesançon, FranceRecruiting
CHU Bordeaux - GH PellegrinBordeaux, FranceRecruiting
CHRU La Cavale BlancheBrest, FranceRecruiting
HCL-Groupement Hospitalier Lyon EstBron, FranceRecruiting
CHU Côte de NacreCaen, FranceRecruiting
CHU Clermont FerrandClermont-Ferrand, FranceRecruiting
CH Sud FrancilienCorbeil-Essonnes, FranceRecruiting
Hôpital Henri MondorCréteil, FranceRecruiting
CHU Dijon-Hôpital François MitterrandDijon, FranceRecruiting
Hôpital Raymond PoincaréGarches, FranceRecruiting

+ 30 more locations — full list on the registry record.

Follow this study

Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.

We email about this public record only. Unsubscribe anytime with one click. Never medical advice.

Is this your study? This page was generated automatically from the public registry record. Sponsors can claim it — free — to add branding and verified contact routing. Claim this page →

This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.

Source record: clinicaltrials.gov/study/NCT05387954