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Study identifier: NCT05384769 Synced from ClinicalTrials.gov · July 28, 2026
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Feasibility of Cell-Free DNA Liquid Biopsy in Screening High-Risk Patients for Lung Cancer

Condition: Lung Carcinoma  ·  Sponsor: City of Hope Medical Center

PhaseNA
Planned participants108
Who can joinAll sexes, 50 Years to 80 Years
Healthy volunteersYes

About this study

This clinical trial investigates how practical and doable (feasibility) cell-free deoxyribonucleic acid (DNA) liquid biopsy is in screening high-risk patients for lung cancer. Currently, a low dose computed tomography (CT) scan is used to screen for lung cancer, however, due to various factors, few high-risk patients are screened. Liquid biopsy utilizes technology that can detect small amounts of DNA shed by cancer cells and may be able to spot lung cancer at an earlier stage. If a positive result comes back from the liquid biopsy, a patient may be more willing to get a low dose CT (LDCT) scan, possibly confirming the biopsy's findings and thus leading to more early lung cancer detection.

This description comes directly from the study's public registry record.

Talk to the study team

Dan Raz, MD  ·  626-359-8111  ·  draz@coh.org

Always discuss trial participation with your own doctor first.

Locations (1)

City of Hope Medical CenterDuarte, California, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05384769