Condition: Tuberculous Meningitis · Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
The purpose of this study is to compare a 6-month regimen of high-dose rifampicin (RIF), high-dose isoniazid (INH), linezolid (LZD), and pyrazinamide (PZA) versus the World Health Organization (WHO) standard of care (SOC) treatment for tuberculosis meningitis (TBM).
This description comes directly from the study's public registry record.
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| Hospital Nossa Senhora da Conceicao CRS (Site ID: 12201) | Porto Alegre, Brazil | Recruiting |
| Instituto de Pesquisa Clinica Evandro Chagas (IPEC) CRS (Site ID: 12101) | Rio de Janeiro, Brazil | Recruiting |
| Byramjee Jeejeebhoy Government Medical College (BJMC) CRS (Site ID: 31441) | Pune, India | Recruiting |
| Moi University Clinical Research Center (MUCRC) CRS (Site ID: 12601) | Eldoret, Kenya | Recruiting |
| Kenya Medical Research Institute/Walter Reed Project Clinical Research Center (KEMRI/WRP) CRS (Site ID: 12501) | Kericho, Kenya | Recruiting |
| Malawi CRS (Site ID: 12001) | Lilongwe, Malawi | Recruiting |
| Nutrición-Mexico CRS (Site ID: 32078) | Mexico City, Mexico | Not Yet Recruiting |
| Socios en Salud Sucursal Peru CRS (Site ID: 31985) | Lima, Peru | Not Yet Recruiting |
| Barranco CRS (Site ID:11301) | Lima, Peru | Not Yet Recruiting |
| TB HIV Innovations and Clinical Research Foundation Corp (Site ID: 31981) | Cavite, Philippines | Not Yet Recruiting |
| Durban International CRS (Site ID:11201) | Durban, South Africa | Not Yet Recruiting |
| University of the Witwatersrand Helen Joseph (WITS HJH) CRS (Site ID: 11101) | Johannesburg, South Africa | Not Yet Recruiting |
+ 6 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT05383742