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Study identifier: NCT05379985 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS

Condition: Non-small Cell Lung Cancer (NSCLC) · Colorectal Cancer (CRC) · Pancreatic Ductal Adenocarcinoma (PDAC)  ·  Sponsor: Revolution Medicines, Inc.

PhasePhase 1/Phase 2
Planned participants754
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Evaluate the safety and tolerability of RMC-6236 in adults with specific RAS mutant advanced solid tumors.

This description comes directly from the study's public registry record.

Talk to the study team

Revolution Medicines, Inc.  ·  1-844-273-8633  ·  medinfo@revmed.com

Always discuss trial participation with your own doctor first.

Locations (21)

UC Irvine/Chao Family Comprehensive Cancer CenterOrange, California, United StatesRecruiting
UCLASanta Monica, California, United StatesRecruiting
Moffitt Cancer CenterTampa, Florida, United StatesRecruiting
Piedmont HealthcareAtlanta, Georgia, United StatesRecruiting
Mary Bird Perkins Cancer CenterBaton Rouge, Louisiana, United StatesRecruiting
Johns Hopkins UniversityBaltimore, Maryland, United StatesRecruiting
Dana Farber Cancer InstituteBoston, Massachusetts, United StatesRecruiting
Perlmutter Cancer Center at NYU Langone HealthNew York, New York, United StatesRecruiting
Memorial Sloan-Kettering Cancer CenterNew York, New York, United StatesRecruiting
Columbia UniversityNew York, New York, United StatesRecruiting
Christ Hospital Cancer CenterCincinnati, Ohio, United StatesRecruiting
Taylor Cancer Research CenterMaumee, Ohio, United StatesRecruiting

+ 9 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT05379985