● Recruiting

Multinational Phase II Trial to Compare Safety and Efficacy of SIRT (Y-90 Resin Microspheres) Followed by Atezolizumab Plus Bevacizumab, vs SIRT (SIRT-Y90) Followed by Placebo in Locally Advanced HCC Patients

Condition: Locally Advanced Hepatocellular Carcinoma · Sponsor: National Cancer Centre, Singapore

PhasePhase 2

Planned participants100

Who can joinAll sexes, 21 Years to 99 Years

Healthy volunteersNo

About this study

This is a multi-national, phase II, parallel-arm, double-blind, placebo-controlled, two-arm study designed to assess the efficacy and safety of SIRT-Y90 followed by atezolizumab plus bevacizumab \[study arm\], versus SIRT-Y90 followed by placebo \[control arm\] in patients with locally advanced Hepatocellular Carcinoma (HCC).

This description comes directly from the study's public registry record.

Talk to the study team

Professor Pierce CHOW, MD, PhD · +65 6436 8000 · pierce.chow.k.h@singhealth.com.sg

Vennese LOW · +65 6306 5456 · low.minxiu.vennese@nccs.com.sg

Always discuss trial participation with your own doctor first.

Locations (14)

Beijing Tsinghua Changgung Hospital	Beijing, China	Recruiting
People's Liberation Army General Hospital (1st and 6th Medical Centre)	Beijing, China	Not Yet Recruiting
West China Hospital, Sichuan University	Chengdu, China	Recruiting
Shandong Cancer Hospital	Jinan, China	Not Yet Recruiting
National University Hospital	Singapore, Singapore	Recruiting
National Cancer Centre Singapore	Singapore, Singapore	Recruiting
Samsung Medical Center	Seoul, South Korea	Recruiting
Seoul National University Hospital	Seoul, South Korea	Recruiting
Severance Hospital Yonsei University Health System	Seoul, South Korea	Recruiting
Kaohsiung Chang Gung Memorial Hospital	Kaohsiung City, Taiwan	Recruiting
Taichung Veterans General Hospital	Taichung, Taiwan	Recruiting
National Taiwan University Cancer Center	Taipei, Taiwan	Recruiting

+ 2 more locations — full list on the registry record.

Follow this study

Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.

We email about this public record only. Unsubscribe anytime with one click. Never medical advice.

Is this your study? This page was generated automatically from the public registry record. Sponsors can claim it — free — to add branding and verified contact routing. Claim this page →

This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.

Source record: clinicaltrials.gov/study/NCT05377034