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Study identifier: NCT05375266 Synced from ClinicalTrials.gov · July 29, 2026
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Immune Biomarker Study for Head and Neck Cancer

Condition: Head and Neck Cancer · Oral Cavity Cancer · Oropharyngeal Cancer  ·  Sponsor: University of Erlangen-Nürnberg Medical School

PhaseN/A
Planned participants1100
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The aim of this prospective non-interventional multi-center trial is to study the prognostic value of intratumoral and systemic immune biomarkers in newly diagnosed non-metastatic head and neck cancer. Furthermore, the local immunological processes in the tumor will be correlated with the systemic immune status determined in the peripheral blood to identify prognostic immune signatures. In addition, tumor organoids will be generated ex vivo for functional biological analyses. The main objective is to create a prognostic score determined by clusters based on tumor immunologic criteria.

This description comes directly from the study's public registry record.

Talk to the study team

Antoniu-Oreste Gostian, PD Dr. med.  ·  +49 9131 85-33156  ·  antoniu-oreste.gostian@uk-erlangen.de

Always discuss trial participation with your own doctor first.

Locations (3)

ENT - Head and Neck Surgery DepartmentErlangen, Bavaria, GermanyRecruiting
Maxillo-Facial-Surgery DepartmentErlangen, Bavaria, GermanyRecruiting
Radiation Oncology DepartmentErlangen, Bavaria, GermanyRecruiting

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Source record: clinicaltrials.gov/study/NCT05375266