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Study identifier: NCT05369546 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Lesion Composition and Quantitative Imaging Analysis on Breast Cancer Diagnosis

Condition: Breast Cancer  ·  Sponsor: University of Hawaii

PhaseN/A
Planned participants600
Who can joinFemale, 20 Years to 85 Years
Healthy volunteersNo

About this study

The objective is to better identify suspicious breast lesions that need to be biopsied for malignancy in women currently recommended for biopsy. The long-term goal is to reduce unnecessary biopsies and increase biopsy yield. To do this, the investigators have developed an innovative way to use FDA-approved breast imaging protocols to acquire multispectral images to measure the composition of suspicious breast lesions. The central hypothesis is that breast tissue composition in combination with analysis of morphological and textural tissue characteristics on digital breast tomosynthesis (DBT) imaging will yield significantly higher breast cancer specificity than conventional interpretation of DBT alone.

This description comes directly from the study's public registry record.

Talk to the study team

John A Shepherd, PhD  ·  808-440-5234  ·  johnshep@hawaii.edu

Leila Kazemi  ·  808-440-5231  ·  lkazemi@hawaii.edu

Always discuss trial participation with your own doctor first.

Locations (3)

H. Lee Moffitt Cancer Center & Research Institute, Inc.Tampa, Florida, United StatesRecruiting
Hawaii Radiology Associates, LTD (East Hawaii Women's Imaging Center)Hilo, Hawaii, United StatesRecruiting
The Queen's Medical CenterHonolulu, Hawaii, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05369546