Condition: CML, Chronic Phase · CML, Accelerated Phase · Sponsor: Jiangsu Hansoh Pharmaceutical Co., Ltd.
HS-10382 is a small molecular, oral potent, allosteric inhibitor. By binding a myristoyl site of the BCR-ABL1 protein, HS-10382 locks BCR-ABL1 into an inactive conformation. The purpose of this study is to investigate the safety/tolerability and the pharmacokinetic(PK) profile of HS-10382 in patients with chronic myeloid leukemia (CML). Anti-CML activity will also be investigated in this study.
This description comes directly from the study's public registry record.
Yu Hu · 13986183871 · dr_huyu@126.com
Always discuss trial participation with your own doctor first.
| Union Hospital affiliated to Tongji Medical College of Huazhong University of Science and Technology | Wuhan, Hubei, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT05367700