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Study identifier: NCT05361941 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Multicenter Trial of Antibiotic Eluting Graft for Promoting New Bone Growth in/Near Infected Bone Cavities

Condition: Periprosthetic Joint Infections  ·  Sponsor: Elute, Inc.

PhaseNA
Planned participants204
Who can joinAll sexes, 22 Years to no upper limit
Healthy volunteersYes

About this study

This is a pivotal, prospective, multi-center, randomized, concurrent control, patient and assessor-blinded study with two arms: a treatment arm (where subjects will be treated with the EP Granules + Tobramycin (EP G + T) investigational device, a combination device + antibiotic, in the 1st stage of a staged revision for periprosthetic joint infection (PJIs), and a control arm (where subjects are treated with the standard-of-care revision for infected PJIs).

This description comes directly from the study's public registry record.

Talk to the study team

Ashok Khandkar, PhD  ·  801-410-4330  ·  ak@elutinc.com

Eva Serio, BS  ·  801-410-4330  ·  eva@elutinc.com

Always discuss trial participation with your own doctor first.

Locations (16)

University of Southern CaliforniaLos Angeles, California, United StatesRecruiting
Georgetown University Medical CenterWashington D.C., District of Columbia, United StatesRecruiting
Endeavor Health Skokie HospitalSkokie, Illinois, United StatesRecruiting
OrthoIndyIndianapolis, Indiana, United StatesRecruiting
Sinai HospitalBaltimore, Maryland, United StatesRecruiting
Massachusetts General HospitalBoston, Massachusetts, United StatesNot Yet Recruiting
Brigham & Womens HospitalBoston, Massachusetts, United StatesCompleted
U Michigan Medical CenterAnn Arbor, Michigan, United StatesRecruiting
Hospital for Special SurgeryNew York, New York, United StatesRecruiting
OrthoCarolinaCharlotte, North Carolina, United StatesRecruiting
Sanford South University Medical CenterFargo, North Dakota, United StatesWithdrawn
JIS OrthopedicsColumbus, Ohio, United StatesRecruiting

+ 4 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT05361941