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Study identifier: NCT05357846 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

PD-1 Inhibitor Combined With Neoadjuvant Chemoradiotherapy Plus Surgery for Locally Advanced ESCC (NEOCRTEC2101)

Condition: Squamous Cell Esophageal Carcinoma · Esophageal Cancer · Oesophageal Cancer  ·  Sponsor: Sun Yat-sen University

PhasePhase 3
Planned participants422
Who can joinAll sexes, 18 Years to 70 Years
Healthy volunteersNo

About this study

The primary objective is to compare PD-1 inhibitor combined with preoperative chemoradiotherapy followed by surgery versus neo-adjuvant chemoradiotherapy followed by surgery, in terms of the overall survival time (OS) in patients with Stage T1-4aN1-3M0 or T3-4aN0M0 squamous cell esophageal carcinoma.

This description comes directly from the study's public registry record.

Talk to the study team

HONG YANG, M.D. Ph.D.  ·  8602087343  ·  yanghong@sysucc.org.cn

Always discuss trial participation with your own doctor first.

Locations (1)

Sun Yat-sen University Cancer CenterGuangzhou, Guangdong, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT05357846