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Study identifier: NCT05357781 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Immunoglobulin Deficiency a Treatable Cause of Fatigue in Patients With Multiple Sclerosis (MS)?

Condition: Hypogammaglobulinemia · Multiple Sclerosis · Fatigue  ·  Sponsor: Insel Gruppe AG, University Hospital Bern

PhaseN/A
Planned participants106
Who can joinAll sexes, 18 Years to 65 Years
Healthy volunteersNo

About this study

The investigators hypothesize that hypogammaglobulinemia (defined as IgG serum concentration \<7.0g/L) is a treatable cause of fatigue in people with MS: The primary objective is to prove the link between hypogammaglobulinemia and fatigue in patients with multiple sclerosis. The secondary objective is to show that fatigue is mediated via frequent infections in people with MS and hypogammaglobulinemia.

This description comes directly from the study's public registry record.

Talk to the study team

Lara Diem, MD  ·  0041316327000  ·  larafrancesca.diem@insel.ch

Always discuss trial participation with your own doctor first.

Locations (1)

University Hospital of Bern InselspitalBern, Canton of Bern, SwitzerlandRecruiting

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Source record: clinicaltrials.gov/study/NCT05357781