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Study identifier: NCT05357612 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Characterization of the Serotonin 2A Receptor Selective PET Tracer [18F]MH.MZ in Patients With Neurodegenerative Diseases

Condition: Neurodegenerative Diseases · Parkinson Disease · Parkinson Disease Psychosis  ·  Sponsor: Vanderbilt University Medical Center

PhasePhase 4
Planned participants75
Who can joinAll sexes, 50 Years to 85 Years
Healthy volunteersYes

About this study

It is hypothesize that patients with clinically diagnosed neurodegenerative diseases will have significantly different receptor occupancy of 5HT2A receptors compared to a healthy age/sex-matched control group. This will be tested by measuring 5HT2A receptor density using the PET radioligand (R)-\[18F\]MH.MZ in both populations.

This description comes directly from the study's public registry record.

Talk to the study team

Levi Pettit, BA  ·  6154210569  ·  levi.f.pettit@vumc.org

Katie Hay, MS  ·  kaitlyn.r.hay@vumc.org

Always discuss trial participation with your own doctor first.

Locations (1)

Vanderbilt University Medical CenterNashville, Tennessee, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05357612