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Study identifier: NCT05357170 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Microbiome Dysfunction in Surgical Intensive Care Unit Survivors

Condition: Sepsis, Trauma Injury  ·  Sponsor: University of Florida

PhaseN/A
Planned participants468
Who can joinAll sexes, 18 Years to 110 Years
Healthy volunteersYes

About this study

Oral and gastrointestinal microbiome dysfunction has been demonstrated to be a culprit of various systemic dysfunctions in peripheries such as cardiovascular, nervous, endocrine and musculoskeletal systems. The topic of microbiome dysfunction after surgical intensive care admission is understudied but may be responsible for persistent systemic inflammation clinically observed in surgical intensive care patients. Therefore, the objective of this project is to investigate the oral and gut microbiome after the acute phase of sepsis, severe trauma injury, cardiopulmonary bypass, and major vascular surgery to compare with 108 age-matched healthy population controls

This description comes directly from the study's public registry record.

Talk to the study team

Ruth Davis, BSN  ·  352-273-8759  ·  ruth.davis@surgery.ufl.edu

Jennifer Lanz, MSN  ·  352-273-5497  ·  jennifer.lanz@surgery.ufl.edu

Always discuss trial participation with your own doctor first.

Locations (1)

UF Health at Shands HospitalGainesville, Florida, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05357170