← Eichor
Study identifier: NCT05351593 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Tafasitamab Plus Lenalidomide in Relapsed CNS Lymphoma

Condition: CNS Lymphoma · Primary Central Nervous System Lymphoma · Secondary Central Nervous System Lymphoma  ·  Sponsor: James Rubenstein

PhasePhase 1/Phase 2
Planned participants35
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a single arm open-label multicenter phase I/II investigation of combination lenalidomide/Tafasitamab in patients with relapsed central nervous system (CNS) lymphoma. This is the first study to examine a naked anti-CD19 monoclonal antibody in relapsed CNS lymphoma patients as well as the combination of anti-CD19 antibody plus an Immunomodulatory imide drugs (IMiDs) in CNS lymphomas. This study will also test the novel hypothesis that Tafasitamab enhances blood-brain barrier permeability, a potential property that could have broad clinical implications.

This description comes directly from the study's public registry record.

Talk to the study team

UCSF Hematopoietic Malignancies Clinical Trial Recruitment  ·  877-827-3222  ·  HDFCCC.Heme@ucsf.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of California, San FranciscoSan Francisco, California, United StatesRecruiting

Follow this study

Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.

We email about this public record only. Unsubscribe anytime with one click. Never medical advice.

Is this your study? This page was generated automatically from the public registry record. Sponsors can claim it — free — to add branding and verified contact routing. Claim this page →

This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.

Source record: clinicaltrials.gov/study/NCT05351593