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Study identifier: NCT05350540 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Hypopharynx ICG to Reduce the Fistula Rate in Patients Undergoing Salvage Laryngectomy

Condition: Surgery Site Fistula  ·  Sponsor: University Health Network, Toronto

PhasePhase 2
Planned participants70
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

A laryngectomy involves removing the voice box from the throat. After the voice box has been removed from the throat, the surgeon sews the throat closed. Sometimes part of the throat does not heal and saliva runs out of the throat. This is called a fistula. When a fistula happens, healing takes longer and patients will have to wait to eat and start speaking. The test in this research project is called ICG scan (indocyanine green) and tells the surgeon how much blood is flowing to different parts of the throat. If the test shows that there are parts of your throat that have low blood flow, which will delay healing. Only half of the patients in the study will get the ICG scan. This is so the patients who had the ICG scan can be compared to the patients that did not have the ICG scan to determine if the ICG scan really helps decrease fistulas.

This description comes directly from the study's public registry record.

Talk to the study team

Douglas Chepeha, MD  ·  (416) 340-3082  ·  douglas.chepeha@uhn.ca

Alex Esemezie, BSc  ·  (416) 340-4800  ·  alex.esemezie@uhn.ca

Always discuss trial participation with your own doctor first.

Locations (1)

University Health NetworkToronto, Ontario, CanadaRecruiting

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Source record: clinicaltrials.gov/study/NCT05350540