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Study identifier: NCT05348486 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

FMISO-based Adaptive Radiotherapy for Head and Neck Cancer

Condition: Head and Neck Cancer · Hypoxia · FMISO  ·  Sponsor: University Hospital Olomouc

PhaseNA
Planned participants120
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Hypoxia occurs in about 80% of head and neck tumors. Based on experimental and clinical data, hypoxia is a useful parameter for pretherapeutic stratification. These radioresistant regions can be detected with FMISO PET/CT. Moreover, hypoxic subvolumes of tumors can be evolving as target volumes for radiotherapy ("dose painting") in hypoxia imaging-based dose escalation.

This description comes directly from the study's public registry record.

Talk to the study team

Martin Dolezel, Prof  ·  +420588444295  ·  dolezelm@email.cz

Always discuss trial participation with your own doctor first.

Locations (3)

The Masaryk Memorial Cancer InstituteBrno, CzechiaRecruiting
Radiation oncology department in Palacký University and University Hospital OlomoucOlomouc, CzechiaRecruiting
Faculty Hospital OstravaOstrava, CzechiaRecruiting

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Source record: clinicaltrials.gov/study/NCT05348486