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Study identifier: NCT05345327 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

SGLT2 Inhibitors As First Line Therapy to Prevent Renal Decline in Type 2 Diabetes

Condition: Type 2 Diabetes  ·  Sponsor: The George Institute

PhasePhase 3
Planned participants994
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The aim of the trial is to evaluate the effects of the SGLT2 inhibitor, dapagliflozin, compared to metformin on annual decline in eGFR when used as first line therapy in people with Type 2 Diabetes.

This description comes directly from the study's public registry record.

Talk to the study team

Emma Zhang  ·  +61 2 8052 4337  ·  ezhang1@georgeinstitute.org.au

Sarah Stanton  ·  sstanton@georgeinstitute.org.au

Always discuss trial participation with your own doctor first.

Locations (8)

The George Institute for Global HealthSydney, New South Wales, AustraliaRecruiting
The George Institute for Global HealthBrisbane, Queensland, AustraliaRecruiting
Monash UniversityMelbourne, Victoria, AustraliaRecruiting
National Hospital - GalleGalle, Southern Province, Sri LankaNot Yet Recruiting
National Hospital of Sri Lanka 1Colombo, Sri LankaRecruiting
National Hospital of Sri Lanka 2Colombo, Sri LankaNot Yet Recruiting
Jaffna Teaching HospitalJaffna, Sri LankaRecruiting
Kandy National HospitalKandy, Sri LankaRecruiting

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Source record: clinicaltrials.gov/study/NCT05345327