← Eichor
Study identifier: NCT05339529 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Protective Effect of Thymosin Α1 Against Negative Immune Dysregulation and Organ Dysfunction After Acute Aortic Dissection Surgery (PANDA II)

Condition: Acute Aortic Syndrome · Aortic Dissection Type a  ·  Sponsor: Nanjing Medical University

PhaseNA
Planned participants330
Who can joinAll sexes, 18 Years to 90 Years
Healthy volunteersNo

About this study

Systemic inflammatory response syndrome (SIRS) and multiple organ dysfunction syndrome (MODS) are the major causes of death in patients with acute aortic syndrome (AAS). Therefore, the prevention of SIRS and MODS is of great clinical value, and immunomodulatory therapy with thymosin alpha 1 may be beneficial. This study was designed to test the hypothesis that the administration of thymosin alpha 1 during the acute phase of AAS will result in a reduced incidence of SIRS and MODS.

This description comes directly from the study's public registry record.

Talk to the study team

Hong Liu, MD  ·  8618801281613  ·  DR.HONGLIU@FOXMAIL.COM

Hong-jia Zhang, MD  ·  8601068303105  ·  zhanghongjia722@ccmu.edu.cn

Always discuss trial participation with your own doctor first.

Locations (15)

The First Affiliated Hospital of Bengbu Medical CollegeBengbu, Anhui, ChinaRecruiting
Guangdong Provincial People's HospitalGuangzhou, Guangdong, ChinaRecruiting
The First Affiliated Hospital of Nanjing Medical UniversityNanjing, Jiangsu, ChinaRecruiting
Nanjing First Hospital Nanjing Medical UniversityNanjing, Jiangsu, ChinaRecruiting
Subei People's Hospital of Jiangsu ProvinceYangzhou, Jiangsu, ChinaRecruiting
Qilu Hospital of Shandong UniversityJinan, Shandong, ChinaRecruiting
West China Hospital of Sichuan UniversityChengdu, Sichuan, ChinaRecruiting
The Friendship Hospital of Yili Kazak Autonomous PrefectureKazak, Xinjiang, ChinaRecruiting
The Seventh Affiliated Hospital of Xinjiang Medical UniversityÜrümqi, Xinjiang, ChinaRecruiting
The First Affiliated Hospital of Kunming Medical UniversityKunming, Yunnan, ChinaRecruiting
Beijing Anzhen Hospital Capital Medical UniversityBeijing, ChinaRecruiting
The First Affiliated Hospital of Guangzhou Medical UniversityGuangzhou, ChinaRecruiting

+ 3 more locations — full list on the registry record.

Follow this study

Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.

We email about this public record only. Unsubscribe anytime with one click. Never medical advice.

Is this your study? This page was generated automatically from the public registry record. Sponsors can claim it — free — to add branding and verified contact routing. Claim this page →

This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.

Source record: clinicaltrials.gov/study/NCT05339529