Condition: Continuous Glucose Monitoring · Oral Glucose Tolerance · Insulin Sensitivity · Sponsor: Virginia Polytechnic Institute and State University
Animal and observational research in humans suggest that specific types of non-nutritive sweeteners (NNS) may impair glycemic control. However, whether NNS consumption impacts glucose homeostasis in middle-aged/older adults with prediabetes is unknown, and potential mechanisms by which this could occur have yet to be identified. The overall objective of this R21 proposal is to establish proof-of-concept for alterations in glucose homeostasis following intake of sucralose, but not aspartame, in middle-aged/older adults with prediabetes compared to a eucaloric diet with no NNS.
This description comes directly from the study's public registry record.
Valisa Hedrick, PhD · 540-231-7983 · vhedrick@vt.edu
Elaina Marinik, PhD · 540-231-0923 · emarinik@vt.edu
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| Virginia Tech | Blacksburg, Virginia, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT05337098