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Study identifier: NCT05333328 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

OFS in Premenopausal Node+ Breast Cancer With Low Genomic Risk

Condition: Breast Cancer · Estrogen Receptor Positive Tumor · HER2-negative Breast Cancer  ·  Sponsor: Gangnam Severance Hospital

PhasePhase 4
Planned participants418
Who can joinFemale, 20 Years to 50 Years
Healthy volunteersNo

About this study

Among ER+HER2- premenopausal patients with N1 who undergoes primary breast surgery, we will identify the patients with a genomic low risk using the multigene-assay (OncoFREE®). In these, ovarian function suppression with endocrine therapies including either tamoxifen or aromatase-inhibitors will be administered for 5 years.

This description comes directly from the study's public registry record.

Talk to the study team

Sung Gwe Ahn, M.D.,Ph.D.  ·  0220193370  ·  asg2004@yuhs.ac

Always discuss trial participation with your own doctor first.

Locations (2)

Gangnam Severance HospitalSeoul, Korea, South KoreaRecruiting
Seoul National University HospitalSeoul, South KoreaNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT05333328