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Study identifier: NCT05333250 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Modafinil to Improve Fatiguability

Condition: Cancer-related Cognitive Difficulties · Cancer-related Problem/Condition · Fatigue  ·  Sponsor: Ottawa Hospital Research Institute

PhasePhase 1/Phase 2
Planned participants40
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Cancer-related fatigue (CRF) and cancer-related cognitive impairment (CRCI) are among the most commonly reported disabling symptoms experienced by patients with advanced cancer. However, there are currently limited evidence-based pharmacologic interventions available. The investigators will conduct a Vanguard Randomized Clinical Trial (RCT) to estimate the effect of modafinil in managing CRF and CRCI, and to test the feasibility of carrying out the study.

This description comes directly from the study's public registry record.

Talk to the study team

Shainuka Kannathas, HBSc  ·  (613) 562-6262  ·  shkannathas@ohri.ca

Always discuss trial participation with your own doctor first.

Locations (1)

The Ottawa HospitalOttawa, Ontario, CanadaRecruiting

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Source record: clinicaltrials.gov/study/NCT05333250