● Recruiting

TMS for Exposure Therapy Resistant OCD

Condition: 1 Hz Real rTMS to the Pre-SMA · 1 Hz Sham rTMS to the Pre-SMA · Sponsor: Amsterdam UMC, location VUmc

PhasePhase 3

Planned participants250

Who can joinAll sexes, 18 Years to no upper limit

Healthy volunteersNo

About this study

TETRO is a multi-center placebo-controlled double-blind randomized controlled trial with an intervention phase of 5-7 weeks and a follow-up phase of 12 months in 250 adult (18 years and older) OCD patients who show no/insufficient response to ERP, aiming to establish the cost-effectiveness of low frequency (1 Hz) rTMS to the pre-SMA (compared to sham rTMS to the pre-SMA) as adjuvant treatment to exposure with response prevention (ERP). The treatment consists of 4 times/week rTMS combined with ERP for at least 5 weeks (20 sessions), with optional extension phase of 1 or 2 weeks (maximum of 28 sessions in total).

This description comes directly from the study's public registry record.

Talk to the study team

Odile A van den Heuvel, MD PhD · +31-20-4444444 · oa.vandenheuvel@amsterdamumc.nl

Tjardo S Postma, MD · +31-20-4444444 · tetro@amsterdamumc.nl

Always discuss trial participation with your own doctor first.

Locations (8)

Amsterdam UMC, location VU Medical Center	Amsterdam, North Holland, Netherlands	Recruiting
GGZ inGeest	Amsterdam, Netherlands	Recruiting
Neurocare	Eindhoven, Netherlands	Not Yet Recruiting
Neurocare	Groningen, Netherlands	Not Yet Recruiting
Maastricht UMC+	Maastricht, Netherlands	Not Yet Recruiting
Mondriaan	Maastricht, Netherlands	Not Yet Recruiting
ProPersona	Nijmegen, Netherlands	Not Yet Recruiting
Radboudumc	Nijmegen, Netherlands	Not Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT05331937