Condition: Asthma · Allergic Rhinitis · Cat Allergy · Sponsor: The University of Texas Medical Branch, Galveston
This is a mechanistic, controlled, open-label, single-site study to evaluate the effects of RG-RV16 inoculation on airway mucosal gene expression and airway remodeling in 25 healthy controls (HC), in 25 allergic rhinitis subjects (AR) with cat dander allergy, and in 25 allergic asthmatic subjects (AA) with cat dander allergy. Three groups (HC, AR, and AA) will undergo screening to establish clinical history, will undergo pulmonary function testing (spirometry), and will have blood drawn for clinical characterization (IgE, , ImmunoCAP, CBC and differential), and for assessing the presence of existing neutralizing antibody against RV16. Only those who meet criteria will be permitted to continue into the interventional and run-out phases of the study.
This description comes directly from the study's public registry record.
Lisa Sweeney, RN · 409-747-5871 · lanemeth@utmb.edu
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| University of Texas Medical Branch | Galveston, Texas, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT05331170