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Study identifier: NCT05328999 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Fertility and the Microbiome

Condition: Subfertility · Asthenozoospermia  ·  Sponsor: Medical University of Graz

PhaseN/A
Planned participants300
Who can joinAll sexes, 18 Years to 50 Years
Healthy volunteersNo

About this study

With this study, the investigators want to investigate the microbiome and human papilloma virus (HPV) status of couples with subfertility. The investigators want to gain information about association of female and male microbiome and its impact on fertility. HPV prevalence is high, and its impact on fertility has not been studied intensively. The investigators want to find out whether there is an association between HPV status and subfertility, vaginal and seminal microbiome and HPV status and the prevalence among our subfertile couples. As part of this study, the investigators will perform a randomized placebo controlled double blind pilot study to investigate the association between altered sperm quality (impaired motility and elevated DNA fragmentation index), the seminal microbiome and whether intake of probiotics alters these parameters.

This description comes directly from the study's public registry record.

Talk to the study team

Sarah Feigl, Dr.  ·  004331638580831  ·  s.feigl@medunigraz.at

Always discuss trial participation with your own doctor first.

Locations (1)

Medical University of GrazGraz, Styria, AustriaRecruiting

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Source record: clinicaltrials.gov/study/NCT05328999