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Study identifier: NCT05327933 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Preventing Recurrences of Chronic Subdural Hematoma in Adult Patients by Middle Meningeal Artery Embolization

Condition: Hematoma, Subdural, Chronic  ·  Sponsor: Unfallkrankenhaus Berlin

PhaseNA
Planned participants154
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Patients with a chronic subdural hematoma (cSDH), that is, a blood accumulation between two meninges developing over a long period of time, often have recurrent bleedings after an initial operation. The study aims to show that additional surgery reduces the risk of recurrent bleeding. The additional procedure aims to block small blood vessels in the skull with tiny plastic particles. The small blood vessels are embolized using X-rays and a contrast medium and a fine tube that is inserted into the diseased vessels of the head via the groin. Patients of full age who have undergone burr hole trepanation as a first operation, i.e. a blood drain through a hole in the cranial cavity, can participate in the study. Participating patients are randomly assigned to a control group with treatment according to clinical routine or a treatment group with an additional occlusion of the blood vessels in the skull. In addition, patients can consent to a genetic test to determine the relationship between a coagulation factor and the risk of recurrence of the hematoma. In order to record the test results, check-up examinations are carried out after one and three months.

This description comes directly from the study's public registry record.

Talk to the study team

Johannes Lemcke, PD Dr. med.  ·  00493056813701  ·  johannes.lemcke@ukb.de

Leonie Goelz, Dr. med.  ·  leonie.goelz@ukb.de

Always discuss trial participation with your own doctor first.

Locations (1)

Unfallkrankenhaus BerlinBerlin, State of Berlin, GermanyRecruiting

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Source record: clinicaltrials.gov/study/NCT05327933