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Study identifier: NCT05327699 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Glutamatergic Adaptation to Stress as a Mechanism for Anhedonia and Treatment Response With Ketamine

Condition: Major Depressive Disorder  ·  Sponsor: Emory University

PhaseEARLY_Phase 1
Planned participants140
Who can joinAll sexes, 18 Years to 65 Years
Healthy volunteersYes

About this study

The main purpose of this study is to investigate the effects of ketamine on decision-making and emotion processing in a sample of individuals diagnosed with Major Depressive Disorder (MDD).

This description comes directly from the study's public registry record.

Talk to the study team

Michael Treadway, PhD  ·  (404) 727-7541  ·  ketaminestudy@emory.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Emory UniversityAtlanta, Georgia, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05327699