● Recruiting

Study of DISC-0974 (RALLY-MF) in Participants With Myelofibrosis or Myelodysplastic Syndrome and Anemia

Condition: Myelofibrosis; Anemia · Anemia · Myelofibrosis · Sponsor: Disc Medicine, Inc

PhasePhase 1/Phase 2

Planned participants150

Who can joinAll sexes, 18 Years to no upper limit

Healthy volunteersNo

About this study

This phase 1b/2a open-label study will evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, and clinical activity of DISC-0974 as well as categorize the effects on hematologic response in participants with myelofibrosis or myelodysplastic syndrome and anemia.

This description comes directly from the study's public registry record.

Talk to the study team

Disc Medicine Clinical Trials · (617) 674 9274 · clinicaltrials@discmedicine.com

Always discuss trial participation with your own doctor first.

Locations (28)

Banner MD Anderson	Gilbert, Arizona, United States	Recruiting
City of Hope - Duarte	Duarte, California, United States	Recruiting
City of Hope - Lennar	Irvine, California, United States	Recruiting
University of California, San Francisco	San Francisco, California, United States	Recruiting
University of Colorado Anschutz Medical Campus	Aurora, Colorado, United States	Recruiting
Mayo Clinic Jacksonville	Jacksonville, Florida, United States	Recruiting
Sylvester Cancer Center - U Miami	Miami, Florida, United States	Recruiting
Moffitt Cancer Center	Tampa, Florida, United States	Recruiting
Emory Winship Cancer Institute	Atlanta, Georgia, United States	Recruiting
University of Michigan	Ann Arbor, Michigan, United States	Recruiting
Mayo Clinic Rochester	Rochester, Minnesota, United States	Recruiting
Washington University St.Louis	St Louis, Missouri, United States	Recruiting

+ 16 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT05320198