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Study identifier: NCT05319353 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Study to Evaluate the Safety and Tolerability, Pharmacokinetics, and Antiviral Activity of Maribavir for the Treatment of Cytomegalovirus (CMV) Infection in Children and Adolescents Who Have Received a Hematopoietic Stem Cell Transplant (HSCT) or a Solid Organ Transplant (SOT)

Condition: Cytomegalovirus (CMV)  ·  Sponsor: Takeda

PhasePhase 3
Planned participants80
Who can joinAll sexes, N/A to 17 Years
Healthy volunteersNo

About this study

The main aim of this study is to find out the safety, tolerability and pharmacokinetics (PK) of maribavir for the treatment of CMV infection in children and teenagers after HSCT or SOT and to identify the optimal dose of maribavir using a 200 milligrams (mg) tablet formulation or powder for oral suspension. The participants will be treated with maribavir for 8 weeks. Participants need to visit their doctor during 12-week follow-up period.

This description comes directly from the study's public registry record.

Talk to the study team

Takeda Contact  ·  +1-877-825-3327  ·  medinfoUS@takeda.com

Always discuss trial participation with your own doctor first.

Locations (53)

Nemours Children's Health - Wilmington - PINWilmington, Delaware, United StatesRecruiting
Johns Hopkins All Children's Hospital - Main - PINSt. Petersburg, Florida, United StatesRecruiting
Ann and Robert H Lurie Childrens Hospital of Chicago - PINChicago, Illinois, United StatesRecruiting
University of Nebraska Medical Center -985400 Nebraska Medical CenterOmaha, Nebraska, United StatesRecruiting
Cincinnati Children's Hospital Medical Center - PINCincinnati, Ohio, United StatesRecruiting
Cook Children's Health Care SystemFort Worth, Texas, United StatesRecruiting
University of Texas MD Anderson Cancer Center - 1515 Holcombe BlvdHouston, Texas, United StatesRecruiting
Texas Children's Hospital - Wallace Tower - PINHouston, Texas, United StatesRecruiting
Minderoo Children's Comprehensive Cancer CentreRandwick, New South Wales, AustraliaRecruiting
Queensland Children's HospitalWoollangabba, Queensland, AustraliaRecruiting
Royal Children's Hospital Melbourne - PINParkville, Victoria, AustraliaRecruiting
Perth Children's HospitalNedlands, Western Australia, AustraliaRecruiting

+ 41 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT05319353