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Study identifier: NCT05315726 Synced from ClinicalTrials.gov · July 28, 2026
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The Effects of Muscle Vibration on the Development of Spasticity and Neuroplasticity in a Post-stroke Population

Condition: Post-stroke Patient in Acute, Sub-acute Phase or Chronic  ·  Sponsor: Centre Hospitalier Universitaire Dijon

PhaseNA
Planned participants165
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Several studies have recently tested the use of muscle vibration for the rehabilitation of patients after a stroke. When applied in a repeated and focused manner, this vibration appears to promote the recovery of functional capacities through the mechanisms of neuromuscular plasticity. These results are encouraging, showing in particular a significant decrease in spasticity in post-stroke patients in the chronic phase (\> 6 months after stroke), on the upper and/or lower limbs. However, very few studies have been done on this type of early intervention. Muscle vibration may therefore be an innovative therapy to complement the care that is currently offered in the acute and subacute phase of post-stroke rehabilitation. Moreover, brain plasticity after a stroke is particularly high in the 3 months after the accident, but the vast majority of studies having evaluated the impact of vibration in a chronic phase (\> 12 months post-stroke). It is likely, however, that the influence of vibration, particularly on brain plasticity, is increased in the acute or subacute phase (first 6 months). To date, the effect of vibration on spinal cord or cortical plasticity has not been quantified in the acute or subacute phase. This is why the second part of this project (phase 2) aims to systematically evaluate and quantify the neuroplastic and functional effects of post-stroke vibration in the early phase. Phase 1 - Validation of a method for measuring spasticity (upper limb) with an isokinet…

This description comes directly from the study's public registry record.

Talk to the study team

Sophie JULLIAND  ·  03.80.66.94.82  ·  sophie.julliand@chu-dijon.fr

Always discuss trial participation with your own doctor first.

Locations (2)

SSR Marguerite BOUCICAUTChalon-sur-Saône, FranceRecruiting
Chu Dijon BourgogneDijon, FranceRecruiting

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Source record: clinicaltrials.gov/study/NCT05315726