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Study identifier: NCT05313620 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Effect of Tofacitinib on Coagulation and Platelet Function, and Its Role in Thromboembolic Events

Condition: Ulcerative Colitis · Thromboembolism  ·  Sponsor: Fundación de Investigación Biomédica - Hospital Universitario de La Princesa

PhasePhase 4
Planned participants30
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersYes

About this study

Post-authorization, prospective and unicenter clinical trial, in which patients with UC will be included. The treatment with anti-TNFα (infliximab, adalimumab or golimumab) or JAK-inhibitors (tofacitinib) will be initiated by clinical practice and the choice will be made at the discretion of the investigator at the center where the patients will be recruited (Hospital Universitario de La Princesa). In the case of the group of patients treated with tofacitinib, the selection will be made following the action protocol implemented in our center, in which this drug is usually reserved for those cases refractory to anti-TNFα and/or vedolizumab. There will be no random assignment of treatment. The drugs will be used in the approved indications and conditions of use.

This description comes directly from the study's public registry record.

Talk to the study team

Sandra Hermida  ·  913093911  ·  sandra.hermida.hlp@gmail.com

Always discuss trial participation with your own doctor first.

Locations (1)

Hospital Universitario de La PrincesaMadrid, Madrid, SpainRecruiting

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Source record: clinicaltrials.gov/study/NCT05313620