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Study identifier: NCT05310643 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Nivolumab and Ipilimumab in Anti-PD1-Resistant dMMR/MSI mCRC

Condition: Metastatic Colorectal Cancer  ·  Sponsor: GERCOR - Multidisciplinary Oncology Cooperative Group

PhasePhase 2
Planned participants30
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

NIPIRESCUE evaluates nivolumab and ipilimumab in patients with MSI/dMMR mCRC resistant to anti-PD1 monotherapy and previously treated with fluoropyrimidine, oxaliplatine, irinotecan, and anti- vascular endothelial growth factor (VEGF) or anti- epidermal growth factor receptor (EGFR) therapy.

This description comes directly from the study's public registry record.

Talk to the study team

Marie Line GARCIA LARNICOL, MD  ·  01 40 29 85 00  ·  marie-line.garcia-larnicol@gercor.com.fr

Always discuss trial participation with your own doctor first.

Locations (9)

CHU Jean MinjozBesançon, FranceRecruiting
Institute BergonieBordeaux, FranceRecruiting
CHRU LilleLille, FranceRecruiting
CHU DupuytrenLimoges, FranceRecruiting
Centre Léon BérardLyon, FranceRecruiting
ICM Val d'AurelleMontpellier, FranceRecruiting
Centre Antoine LacassagneNice, FranceRecruiting
Hôpital Saint AntoineParis, FranceRecruiting
CHU PoitiersPoitiers, FranceRecruiting

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Source record: clinicaltrials.gov/study/NCT05310643