Condition: HPV · Oropharynx Cancer · HPV-Related Carcinoma · Sponsor: Memorial Sloan Kettering Cancer Center
This study will look at whether monitoring HPV ctDNA levels is an effective way to detect cancer relapse risk in people with HPV-OPC. All participants will have recently had surgery to treat their disease, or they will be scheduled to have this surgery. In Arm A the researchers will see whether monitoring participants' HPV ctDNA levels can safely identify patients who do not need radiation therapy (RT) after surgery and whose RT can be delayed until their HPV ctDNA levels become detectable. In Arm B, the researchers will see whether patients who usually need 6-6.5 weeks of CRT can be selected by HPV ctDNA to receive 3 weeks of CRT.
This description comes directly from the study's public registry record.
Acharf Shamseddine, MD · 631-623-4272 · shamseda@mskcc.org
Nancy Lee, MD · 212-639-3341 · leen2@MSKCC.ORG
Always discuss trial participation with your own doctor first.
| Baptist Alliance MCI (Data Collection Only) | Miami, Florida, United States | Recruiting |
| Memorial Sloan Kettering Basking Ridge (Limited protocol activities) | Basking Ridge, New Jersey, United States | Recruiting |
| Memorial Sloan Kettering Monmouth (Limited Protocol Activities) | Middletown, New Jersey, United States | Recruiting |
| Memorial Sloan Kettering Bergen (Limited Protocol Activities) | Montvale, New Jersey, United States | Recruiting |
| Memorial Sloan Kettering Suffolk-Commack (Limited Protocol Activities) | Commack, New York, United States | Recruiting |
| Memorial Sloan Kettering Westchester (Limited Protocol Activites) | East White Plains, New York, United States | Recruiting |
| Memorial Sloan Kettering Cancer Center (All Protocol Activities) | New York, New York, United States | Recruiting |
| Memorial Sloan Kettering Nassau (Limited protocol activities) | Rockville Centre, New York, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT05307939