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Study identifier: NCT05307289 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Study of Alterations in Tumor Metabolism Associated With the Development of Immunotherapy Resistance in Melanoma

Condition: Melanoma (Skin)  ·  Sponsor: Centre Hospitalier Universitaire de Nice

PhaseNA
Planned participants20
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Among the mechanisms responsible for resistance to immunotherapy, metabolism seems to play a major role. A better understanding of tumor metabolism appears to be absolutely necessary in order to propose efficient therapeutic alternatives to target tumor cells without exerting a deleterious effect on the cells responsible for the anti-tumor immune response. The main objective is to evaluate metabolism modulations in melanoma cells extracted from metastases of patients sensitive and resistant to immunotherapies (anti-PD1 or anti-PD1+anti-CTLA4).

This description comes directly from the study's public registry record.

Talk to the study team

Montaudie Henri  ·  +33492036488  ·  montaudie.h@chu-nice.fr

Always discuss trial participation with your own doctor first.

Locations (1)

CHU de NiceNice, Alpes-maritimes, FranceRecruiting

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Source record: clinicaltrials.gov/study/NCT05307289