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Study identifier: NCT05305924 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Fulvestrant+Abemaciclib With Run-In of Fulvestrant in Er-Positive, Her2-Negative Metastatic Breast Cancer

Condition: ER-Positive Breast Cancer · HER2-negative Breast Cancer  ·  Sponsor: The Methodist Hospital Research Institute

PhasePhase 2
Planned participants28
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The study will investigate if CDK4/6 inhibitor holiday will reset the cell cycle process to respond to the combination of fulvestrant and abemaciclib, and this approach may represent an effective therapeutic strategy to manage such patients.

This description comes directly from the study's public registry record.

Talk to the study team

Polly Niravath, MD  ·  713-441-0629  ·  ccresearch@houstonmethodist.org

Always discuss trial participation with your own doctor first.

Locations (1)

Houston Methodist Cancer CenterHouston, Texas, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05305924