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Study identifier: NCT05304286 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Psychophysical and Neural Mechanisms Contributing to Chronic Post-Surgical Pain in Adolescents and Adults

Condition: Chronic Post-surgical Pain  ·  Sponsor: Massachusetts General Hospital

PhaseNA
Planned participants110
Who can joinAll sexes, 12 Years to no upper limit
Healthy volunteersNo

About this study

The current project will (1) enhance our understanding of the neurobiology of chronic post-surgical pain (CPSP); (2) provide a metric to follow patients with CPSP in the clinic; (3) provide a metric for those who will chronify; and (4) understand the age-related differences in CPSP. Ultimately, an improved comprehension of mechanisms linked to CPSP will provide finer tools for optimizing the selection of treatments for individual patients. Moreover, data that demonstrates the underlying pathobiological pain mechanism(s) active in CPSP, particularly those non-responsive to current therapies, may be used to validate novel strategies both pharmacological and non-pharmacological.

This description comes directly from the study's public registry record.

Talk to the study team

Christine B Sieberg, PhD  ·  6177261654  ·  csieberg@mgh.harvard.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Massachusetts General HospitalBoston, Massachusetts, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05304286